The Cutaneous Adverse Events at the Site of Insulin Injections

Cutaneous adverse events at the site of insulin injections include local allergic reactions to insulin (erythema, pruritus, and induration) and lipodystrophy The allergic reactions are usually short-lived, and resolve spontaneously within a few weeks [1]. Lipodystrophies are a group of diseases characterised by a morphological and/or functional impairment of the adipose tissue. Classification of lipodystrophy include genetic and acquired forms. Acquired forms can be generalized (Lawrence syndrome), partial (Barraguer-Simons syndrom, associated with sclerodermia or acquired immunodeficiency syndrome and antiretroviral therapy), or local (associated with drug: glucocorticoids, post-injection-insulin, somatostatin analogs, pegvisomant)[2]. Clinical forms of lipodystrophy include lipoatrophy and lipohypertrophy. […]