The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

Radu Valeriu Toma

Radu Valeriu Toma

Cardiotoxicity of Multimodal Treatment for Breast Cancer

In the era of the optimal and the personalized oncological treatments, life expectancy increases, therewith the need of understanding and managing side effects is a challenging task.
The most notable research advances in breast cancer involve new radiation treatments techniques and targeted therapies.
Cardiac toxicity following radiotherapy (RT) is recognized as an important issue. Furthermore, with the prevalent and necessary treatment with anthracyclines and trastuzumab, which carry an independent and confirmed risk of cardiotoxicity[1-3] the additional heart disease risk following radiotherapy must be kept to a minimum. [...]

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Metachronous Cancers

According to GLOBOCAN, cervical cancer is the fourth most common cancer worldwide touching woman, with approximately around 500000 new cases and 266000 deaths in 2012; in Romania, cervical cancer is the second malignancy diagnosed in women. Cervical cancer is responsible for 7.5% from the whole female cancer deaths and 87% of these cases are encountered in the less developed regions of the world. The more advanced is the stage of cervical cancer, the worse the prognosis is and the treatment in these cases is mainly palliative with an average survival period of only 7 years as observed in recurrent and/or metastatic cancer [...]

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