The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

Ovidiu Bulzan

Ovidiu Bulzan

Acute Hepatic Porphyria – Minireview

Acute Hepatic Porphyria (AHP) is an uncommon and hereditary illness that belongs to a group of disorders known as porphyries. This condition results from a deficiency of the porphobilinogen deaminase enzyme, which plays a role in heme production, a crucial component of haemoglobin in the bloodstream. This deficiency leads to the accumulation of substances called porphyrins in the body, which can trigger the appearance of severe and
potentially life-threatening symptoms.
In the following, we will discuss classifications - with a focus on the similarities and differences between subtypes of porphyria, the pathophysiology of acute hepatic porphyria, risk factors – and their influence on the onset of the disease, clinical manifestations, diagnosis, and management – both curative and symptomatic, all of which play a very important role in understanding this rare condition.

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Problems with the Monitoring of Patients with Colonic Polyps

Colorectal neoplasm ranks third in incidence and 4th among the most common causes of cancer death worldwide. In Romania, Arad, of all digestive cancers, colorectal cancer is the No. 3, both in incidence - in both men and women - and mortality. Colorectal cancer incidence is estimated to be 10.1 / 100,000 inhabitants in men and 7.3 / 100,000 inhabitants in women.
This paper is a retrospective statistical study, carried out over a period of 5 years. This study includes the monitoring of patients recorded with colonic polyps, within the area of 4 family physician practices. This study was conducted because there was a decrease of addressability (adherence) of patients recorded with having colonic adenomatous polyps. (1)

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Histopathology and Forensic Diagnostics Difficulties in a Patient with Multiple Affections and Double Cranio-Cerebral Injuries

This paper is a case presentation. This case was chosen because it presented several problems with indicating, with certainty, the cause of death and therefore establishing the tanato-generating mechanism. The patient is a female from the rural environment who dies after a hospitalization (03 March 2013) in the Clinical Emergency Hospital in Arad, Department of Neurology. The patient is admitted through the emergency unit due to a cranio-cerebral trauma in the left parietal-temporal region, assisted respiratory failure and second degree coma.

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