The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

Mircea Stefan Tampa

Mircea Stefan Tampa

Spontaneous Rupture of the Spleen on a Patient with Splenic Hemangioma and Multiple Cystic Lesions in Kidney and Liver...

Splenic hemangioma is a vascular malformation which is one of the most common benign neoplasms of the spleen. They may represent small, incidental lesions that can produce significant splenomegaly and predispose to splenic rupture. These tumors are rare and resemble their counterparts in other organs. The vascular spaces are usually irregular and cavernous, containing abundant red blood cells.
Differential diagnoses include benign or malignant neoplasms, metastases, lymphoma, splenic abscess or cystic lesions. The incidence of autopsy examination of their diagnosis ranges from 0.03 to 14% [1], and most often is encountered in adults between the ages of 30 and 50 [2]. Most are small lesions, usually clinically silent, diagnosed accidentally. Sometimes, however, they may be symptomatic, manifested by splenomegaly, abdominal pain, bowel disorders, anemia and thrombocytopenia, Kasabach-Merritt syndrome (anemia, thrombocytopenia and coagulopathy) and in rare cases by spontaneous rupture of the spleen [3].

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The Ethical Implications of Complementary and Alternative Medicine in Systemic Lupus Erythematosus

Lupus erythematosus is an autoimmune disease with multiple symptoms and each patient presents a particular clinical and immunological-biological profile. The cause of the disease remains unknown. Lupus erythematosus embraces three clinical forms: chronic, subacute and systemic. Events in the three clinical forms range from skin involvement (chronic form) to serious systemic implications, affecting patient's health and life (as a systemic disease).
The systemic form - systemic lupus erythematosus - has a wide range of immunological abnormalities that cause inflammation in various organs and systems. The inflammation occurs as a result of excessive production of autoantibodies, that are directed against self structures that are no longer recognized. In systemic lupus, cutaneous manifestations are often accompanied by renal, cardiac, osteoarticular, neuropsychiatric disorders.

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