Diabetes mellitus brings together several syndromes, all burdened by a high complexity and with the potential to generate vital impairment. The large number of complications result from the association of high blood glucose level with vascular damage, neuropathy, poor healing and overall increased atherosclerosis process. The clinical manifestation of these complications involves a wide range of manifestations from simple lesions to complex pathology, many of them requiring surgical treatment. Surgical implications of diabetes mellitus include diabetic foot syndrome, soft tissue infections, renal impairment and abdominal pathology.

Small cell glioblastoma is a subtype of glioblastoma, an uncommon, with poor prognosis. Due to its rarity, reports of molecular genetics and immunohistochemistry are required to understand the tumor behavior. We report here the clinical history and results of the molecular analysis of a patient diagnosed with small cell glioblastoma.