Synovial sarcomas (SS) are rare. Less than 5% occur in spine, mediastinum, head and neck and at the retroperitoneal level and in approximately 85% of the cases occur at the level of the soft tissues and extremities. SS metastases are not rare, they occur predominantly at the level of lungs, bones and liver. Standard treatment consists in surgery, ideal, in large excision with negative margins, R0 (when is possible). For unresectable tumors, the therapeutic options include CMT and/or RTE [2]. [...]