2014 Volume 21

In the twentieth century, the widespread use of quinacrine by the U.S. military as malaria prophylaxis was accompanied by other observations suggesting efficacy for treatment of rheumatologic diseases [1]. During the 1950s, the hydroxychloroquine (HCQ) derivative of quinacrine showed a […]

Read More… from Multiple Benefic Effects of the Systemic Exposure to the Hydroxychloroquine Sulfate

Hyponatremia, with an incidence of 15 – 22%, is considered when serum sodium levels are < 135 mEq/L (in institutionalized geriatric patients, in 1 – 4% to 7 – 53% cases there have been reported values below 130 mEq/L) [1-3]. […]

Read More… from HYPONATREMIA IN PREDIALYSIS HOSPITALIZED PATIENTS: AN UPDATE ON CLINICAL DATA AND MANAGEMENT

In reconstructive surgery, perforator flaps have a short history. Not more than 27 years ago, Nakajima et al. described the six types of perforator vessels known at present: direct cutaneous, direct septocutaneous, direct cutaneous branch of muscular vessel, perforating cutaneous […]

Read More… from PERFORATORS OF THE CALF ARTERIES – ANATOMICAL STUDY

There are worldwide standardization attempts, through therapeutic guidelines of colon cancer screenings. For a screening to be effective, it must involve a more complex understanding of risk factors, finding effective methods and most importantly to applied en masse at an […]

Read More… from Study Regarding the Distribution and Degree of Dysplasia of Colonic Polyps

Diabetes mellitus is a major health problem with significant impact on the quality of life, due to both its complications and comorbidities and due to the costs it generates. There is widespread agreement that the incidence of the disease has […]

Read More… from Split-thickness Skin Grafting in the Treatment of Surgically Operated Diabetic Foot. A Retrospective 2-Year Study (2010-2011)

Hypertension associates with sudden cardiac death, its relationship with ventricular arrhythmias being demonstrated by numerous studies (1). Multiple mechanisms were proposed in order to explain this association, involving both structural and electrophysiological myocardial changes. The electrical ventricular remodeling includes non-uniform […]

Read More… from Dispersion of Ventricular Repolarization in Relation to Blood Pressure Values in Essential Hypertension