X-linked Lissencephaly: a Smooth Brain and a Rough Journey for a 15-Year-Old-Patient


The cerebral cortex shows a precise layering of multiple neuronal types with distinct form and function, essential for the cognitive functions that define us as humans. Remarkably, cortical neurons are not formed in the cortex itself but in specialized proliferative regions deep in the brain, so that postmitotic neurons must migrate as far as 1000 cell body-lenghts to reach their final destination[1]. […]