The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

The Use of Tranexamic Acid for Preventing Bloodloss During Percutaneous Nephrolithotomy


Percutaneous nephrolithotomy (PCNL) is a minimally invasive method of treatment used for large kidney stones (>20 mm). It remains the standard procedure for large renal calculi according to EAU (European Association of Urology) guidelines. The stones are extracted from the kidney by a small puncture wound (about 1 cm) through the skin. Since its introduction this technique has replaced almost completely open surgery for renal lithiasis, who nowadays is used only rarely in selected cases. Although this procedure has much lower complications than open surgery, the complications following this procedure can be serious[1] (Table 1). Morbidity and complications following PCNL are dominated by fever (10.5%) and bleeding (7.8%)[2]. […]