The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

Radionuclide Imaging. An Update on the Use of Dynamic Renal Scintigraphy


Renal scintigraphy is a nuclear medicine technique that uses medical radioactive isotopes for the evaluation of the renal function. Functional data complete clinical and anatomical data obtained through other imaging techniques and can assist the clinician in the diagnostic and management of various renal disorders.
The most widely used radioactive isotope for me-dical imaging is Technetium-99m. In renal scintigraphy 99m-Tc is coupled to a substance that is eliminated predominantely by glomerular filtration (DTPA) or tubular excretion (MAG3) or which is attached to tubular proteins (DMSA). DTPA and MAG3 allow a dynamic study which result in the generation of a nephrographic curve for each kidney and the calculation of clearance parameters – ie glomerular filtration rate (GFR) or the effective renal plasma flow (ERPF), respectively. […]