Outcome of Children with Acute Lymphoblastic Leukemia Treated with the ALL-BFM 95 Protocol during 2001-2014 at the Pediatric…

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Acute lymphoblastic leukemia (ALL) is responsible for 25% of all childhood cancers. The outcome has dramatically changed during the last decades, reaching an overall survival rate of approximately 80% in high-income countries and lower rates in low and middle-income countries [1-6]. Recent trials with risk stratifi cation based on biological features of leukemic cells and response to therapy report an even better survival rate of 90% [7].