Acute Hepatic Porphyria (AHP) is an uncommon and hereditary illness that belongs to a group of disorders known as porphyries. This condition results from a deficiency of the porphobilinogen deaminase enzyme, which plays a role in heme production, a crucial component of haemoglobin in the bloodstream. This deficiency leads to the accumulation of substances called porphyrins in the body, which can trigger the appearance of severe and
potentially life-threatening symptoms.
In the following, we will discuss classifications - with a focus on the similarities and differences between subtypes of porphyria, the pathophysiology of acute hepatic porphyria, risk factors – and their influence on the onset of the disease, clinical manifestations, diagnosis, and management – both curative and symptomatic, all of which play a very important role in understanding this rare condition.

Colorectal neoplasm ranks third in incidence and 4th among the most common causes of cancer death worldwide. In Romania, Arad, of all digestive cancers, colorectal cancer is the No. 3, both in incidence - in both men and women - and mortality. Colorectal cancer incidence is estimated to be 10.1 / 100,000 inhabitants in men and 7.3 / 100,000 inhabitants in women.
This paper is a retrospective statistical study, carried out over a period of 5 years. This study includes the monitoring of patients recorded with colonic polyps, within the area of 4 family physician practices. This study was conducted because there was a decrease of addressability (adherence) of patients recorded with having colonic adenomatous polyps. (1)