Natalia Turcan

Natalia Turcan

Rare Dermatological Pathologies in Pregnancy. Importance of Early Diagnosis and Multidisciplinary Management

Cellulitis is among the most common skin and soft tissue infections and manifests as an area of skin erythema, warmth and edema as a result of bacterial of the skin barrier. The incidence of cellulitis is about 200 cases/ 100.000 patients per year. In the majority of cases the epidemiological factor are beta-hemolytic streptococci (groups A, B, C, G, and F). Pregnant and postpartum patients have an increased risk for developing invasive infection which typically manifests as toxic shock syndrome, sepsis or necrotizing fasciitis. Onset of cellulitis antepartum is uncommon, most patients being healthy and with uncomplicated pregnancies. We present the case of a 36 years old gravida which presents for her 34 weeks checkup. From the obstetrical point of view all parameters were within normal, the patient being known with a gestational diabetes well controlled through appropriate diet. The patient describes non-specific bilateral inner thigh pain that started approximately 12 hours ago. Further multidisciplinary management establish the diagnosis of acute infectious cellulitis with an excellent outcome due to early diagnosis and specific treatment. The particularity of these case is bilateral cellulite, mirrored on the inner thighs in the third trimester of pregnancy in a woman with no other risk factors other than well-controlled diabetes mellitus, in which childbirth favored a better outcome.

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Uterine Artery Embolization for Uncontrollable Hemorrhage after Vaginal Hysterectomy

Hysterectomy is the most common gynecologic procedure performed all over the world and various complications may appear depending on the surgical route. Delayed postoperative hemorrhage is a rare, life threatening complication. It requires timely management and recently the surgical reinterventions tend to be replaced by minimally invasive techniques. Transcatheter arterial embolization shows good results as a treatment strategy for massive vaginal bleeding post hysterectomy, when vaginal vault suturing fails to achieve hemostasis. We report a case of right uterine artery bleeding occurring 30 days after vaginal hysterectomy that was successfully treated by transcatheter arterial embolization.

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Correlation Between Early Diagnosis of Ovarian Neoplasm and Long-Term Prognosis

Ovarian cancer is the seventh most commonly diagnosed cancer in women, with the highest mortality rate among female genital cancers. Due to the nonspecific symptoms and the lack of effective screening strategies, ovarian cancer is often diagnosed in an advanced stage of the disease, with a 5-year survival rate of 25%. The efforts of specialists are aimed at identifying screening methods, with the lowest possible rates of false positive or false negative results in order to diagnose the disease at an early stage, when the 5-year survival rate is 92%. In this study we analyzed the incidence of ovarian cancer in the last five years in the Bucharest University Emergency Hospital, being registered 153 cases of ovarian cancer. The aim of this paper is to analyze the correlation between the early diagnosis of ovarian cancer and the long-term prognosis.

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Comparative Analysis of Vertical Transmission of SARS-CoV-2 Antibodies in Vaccinated and Non-Vaccinated Pregnant Women

Pregnancy is a risk factor for developing a severe, complicated form of COVID-19. Medical reports have revealed that pregnancy increases three times the risk of ICU admission and 1.7 times the risk of death in patients with COVID-19. The crossing of the placenta by the antibodies generated through vaccination offer a level of protection that should not be ignored. We aimed to comparatively analyze the levels of SARS-CoV-2 IgG and IgM antibodies in pregnant women who have had this infection during pregnancy or have undergone a complete vaccination cycle during pregnancy, as well as antibody levels in newborns. The inclusion criterion was history of SARS-CoV-2 infection during pregnancy or COVID-19 complete vaccination. For each case the peri-partum values of IgG and IgM SARSCoV- 2 antibodies were analyzed in the same laboratory along with those of their newborns. The vaccination rate in our study group was about 6%. All cases had a significant value of protective IgG SARS-CoV-2 antibodies and the level of protective antibodies of the newborns closely followed maternal values. From the cases with SARS-CoV-2 infection during pregnancy, only 16.6% had a protective level of antibodies and 75% of the newborns from these cases had protective levels of IgG SARS-CoV-2 antibodies. Our results clearly plead in favor of vaccination in pregnancy
which provides significant benefits for both mothers and infants.

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