A 6 years old female diagnosed with nephrotic syndrome developed, during her first admission in the hospital, sinus transvers thrombosis. At first it was considered a complication of the disease, but later it was proved that she had hereditary thrombophilia. The major symptom in this case was persistent headache.

Metabolic syndrome (MetS) is defined as a cluster of elements represented by increased levels of fasting plasma glucose, raised tryglicerides, high blood pressure and modified values of HDL cholesterol associated with the presence of abnormal abdominal waist[1,2]. Due to this elements it represents a predicting factor regarding the development of type II diabetes and cardiovascular disease. Although insulin resistance[3] and central obesity[4] represent the main causative factors, there are still many unknown variables of its components that require further research. [...]

Metabolic Syndrome (MetS) represents a group of clinical and biological criteria that when combined can become a potential threat for the development of severe pathologies -diabetes mellitus, cardiovascular disease, obesity. The International Diabetes Federation(IDF) defines the presence of MetS when 3 or more of the following criteria are detected: 1.raised triglycerides ?150 mg/dL (1.7 mmol/L) or specific treatment for this lipid abnormality
2.reduced HDL cholesterol <40 mg/dL (1.03 mmol/L) in males <50 mg/dL (1.29 mmol/L) in females or specific treatment for this lipid abnormality
3.raised blood pressure systolic BP ?130 or diastolic BP ?85 mm Hg or treatment of previously diagnosed hypertension
4.raised fasting plasma glucose, (FPG) ?100 mg/dL (5.6 mmol/L), or previously diagnosed type 2 diabetes
5.central obesity (defined as waist circumference* with ethnicity specific values) (IDF guidelines)[1-3].