Gastrointestinal stromal tumors (GIST) are rarely encountered in medical practice, developing with predilection in people over 40 years old. Their starting point is found in the digestive tract, and can appear anywhere along it. Normally, in the human body cells go through the processes of development, division and then apoptosis. In the case of gastro-intestinal stromal tumors, the cells divide continuously and the process of apoptosis is no longer carried out, forming these tumors, which can be benign or malignant. The essential medical treatment used in the case of gastrointestinal stromal tumors is Imatinib, which has the role of preventing the growth or even regression in size of the tumor in most cases. The specificity marker for GIST is represented by c-KIT protein, and immunohistochemically, the majority of gastrointestinal stromal tumors show positivity for CD34 and c-KIT. There are also extragastro-intestinal stromal tumors, for example located in the liver, duodenum, pancreas, but they are extremely rare, being considered rather as metastases from the primary tumor.

The study aims to evaluate the incidence, characteristics of diagnosis and treatment for patients with rectal cancer, but also the evolution of patients diagnosed with this neoplasia, so that a personalized treatment can be applied and followed, adapted to the patient’s clinical-imaging picture. The study included 127 patients operated on between January 2018 and November 2021. Dixon resection was performed in 63 patients, rectal amputation (Miles) in 42 patients, and Hartmann resection in 22 patients. For the Miles-type intervention, the patients in a more advanced stage were selected, which represented a percentage of 33.07% of the total. This type of intervention involves a permanent colostomy and has a strong impact on the patient’s life. Of the total of 127 patients, the presence of complications was relatively rare, occurring in only 14 patients. Of the 14 patients, the most common complication was abscess, which occurred in 6 patients, while peritonitis and occlusion occurred in only 4 patients. After analyzing the data obtained, it can be seen that the results coincide with world statistics, the highest incidence of rectal cancer occurring in the age range 60-69 years, with an increased incidence among male patients.

As in cervix carcinoma the role of HPV has been proved, infact there is a rare type of PC which is directly linked to HPV[3]. As such, the prevalence of penile neoplasia is related to that of HPV in general population. Strains 16 and 18 are the most common findings in penile carcinoma[4]. [...]