The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

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Monday, November 12 2018 @ 10:11 EET

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A Curious Case of Rhinophyma in a 73-Year-Old Patient

2017-02

Tiberiu Paul Neagu, Khalid Al-Falah, Mirela Tiglis, Iulia Gabriela Marcu, Cristian Radu Jecan, Liliana Elena Mirea, Ioan Lascar

Rhinophyma is a benign tumor characterized by a pro-gressive hypertrophy of the nose soft tissues, with a re-ddish and bulky appearance, affecting most frequently elderly Caucasian males[1], which may also cause functional airway obstruction. It is believed to be the end stage of severe acne rosacea, but the real cause and the exact etiology remain unknown[1]. The male to female ratio of rhinophyma patient varies between 5 to 1 and 30 to 1 [2,3]. The diagnosis is based on the clinical features of this rare and disfiguring disease using Rhinophyma Severity Index Score (RHISI)[4]. The main differential diagnosis is the basal cell carcinoma (BCC), with an occult incidence of 3% to 10% in patients with rhinophyma[1]. [...]

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Prenatal Diagnosis and Genetic Counselling in Turner Syndrome: Case Report and Literature Review

2017-02

Viorica Tudor, Octavia Velicu, Mihai Mitran, Elvira Bratila, Emilia Severin

The first paper describing female patients with Turner syndrome (TS) was published in 1938 by Henry Turner[1]. It was later discovered that in 1930, Otto Ullrich had already reported a case report of a girl with suggestive symptoms of TS[2]. Therefore, the complete name is Ullrich-Turner syndrome.

Turner’s syndrome is a pathology found only in females, characterized by the partial or total absence of a second sex chromosome which leads to a wide range of physical findings that often includes congenital lymphedema, short stature, and gonadal dysgenesis[1]. The physical symptoms depend on the karyotype, as only 50% of Turner patients are 45,X the others displaying mosaics or abnormalities in the second sex chromosome. [...]

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Cardiotoxicity of Multimodal Treatment for Breast Cancer

2017-02

Radu Valeriu Toma, Georgia Luiza Serbanescu, Mihail Alexandru Oprea, Rodica Maricela Anghel

In the era of the optimal and the personalized oncological treatments, life expectancy increases, therewith the need of understanding and managing side effects is a challenging task.

The most notable research advances in breast cancer involve new radiation treatments techniques and targeted therapies.

Cardiac toxicity following radiotherapy (RT) is recognized as an important issue. Furthermore, with the prevalent and necessary treatment with anthracyclines and trastuzumab, which carry an independent and confirmed risk of cardiotoxicity[1-3] the additional heart disease risk following radiotherapy must be kept to a minimum. [...]

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Charcot Foot Diagnosis - Still an Issue?

2017-02

Ion Cocolos, Tiberiu Paul Neagu, Andrei Tudor Ursache, Ioan Cristescu, Mircea Vasile Ghemigian, Liliana Elena Mirea, Gheorghe Ion Popescu

The Lisfranc fracture-dislocation of the foot is uncommon and many cases are misdiagnosed. The Lisfranc lesion involves the medial cuneiform and base of the second metatarsal which are considered to be the keystone of the structural integrity of the midfoot. This joint has a stabilization effect on longitudinal and transverse arches of the foot. A neglected or untreated injury to the Lisfranc joint can lead to secondary arthritis and significant morbidity with disability. Furthermore, it is well known the correlation between pacients with periferic neuropathy and this type of lesion, also known as Charcot Foot[1]. It has been documented to occur as a consequence of various peripheral neuropathies, but diabetic neuropathy has become the most common etiology[2]. [...]

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A Retrospective on the Treatment of Trochanteric Fractures of the Femur in the Bucharest Clinical Emergency Hospital in 2015

2017-02

Fabian Klein, Ioan Cristescu, Florin Safta, Daniel Vilcioiu

Fractures of the proximal femur are some of the most commonly encountered fracture types, especially when talking about elderly patient[1,2]. Apart from the immediate impact on the patient’s health, a more problematic issue is the impact on the quality of life, especially when talking about geriatric patients[3]. Early surgical treatment, combined with early discharge from hospital and a well-tailored rehabilitation program are mandatory for assuring a quick recovery of the patient’s autonomy. It is estimated that every person over the age of 65 has a 10% chance to fall once per year, with the possibility of contracting a proximal femur fracture. [...]

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The Use of Tranexamic Acid for Preventing Bloodloss During Percutaneous Nephrolithotomy

2017-02

Raluca Barbilian, Victor Cauni, Bogdan Mihai, Ioana Buraga, Mihai Dragutescu, Dan Mischianu

Percutaneous nephrolithotomy (PCNL) is a minimally invasive method of treatment used for large kidney stones (>20 mm). It remains the standard procedure for large renal calculi according to EAU (European Association of Urology) guidelines. The stones are extracted from the kidney by a small puncture wound (about 1 cm) through the skin. Since its introduction this technique has replaced almost completely open surgery for renal lithiasis, who nowadays is used only rarely in selected cases. Although this procedure has much lower complications than open surgery, the complications following this procedure can be serious[1] (Table 1). Morbidity and complications following PCNL are dominated by fever (10.5%) and bleeding (7.8%)[2]. [...]

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The Value of Computed Tomography in Establishing the Proper Surgical Treatment of a Complex Proximal Humerus Fracture

2017-02

Razvan Turcu, Marius Moga, Mircea Ifrim

Proximal humerus fractures result from indirect trauma, are associated with osteoporosis, and are classified into: humeral head fractures, anatomical cervical fractures, trochiter, trochin, surgical neck, or proximal diaphysis. Types of fracture and displacement are determined by the position of the humerus at the time of trauma, bone quality and the direction of muscle forces on fractured fragments[1,2].

Fractures with two, three or four shifted parts require surgical treatment. The dislocation fractures, except for the simple trohiter fractures, should be analyzed by the orthopedic surgeon, the reduction of the dislocation will precede the treatment of the fracture. It should be emphasized that powerful damping maneuvers can move fractured fragments, so it will be preferable to reduce it under radiological control[14]. [...]

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The Role of Psoas Compartment Block in the Management of Pain During and After Total Hip Arthroplasty

2017-02

Bianca Basgan, Nicolae Iordache, Dragos Cocos

The "Psoas Compartment Block" technique was described for the first time in 1974 by the American doctor Alon P. Winnie, in a revolutionary article for that time[1], that was detailing both the anterior approach of the lumbar plexus (3 in 1 Block or femoral nerve block), and the posterior approach.

Subsequently, doctors Chayen D., Nathan H. and Chayen M. are making a series of additions and practical indications, in an article about the posterior approach, entitled "The Psoas Compartment Block"[2], and the technique presented in this article also constitutes the basis for this study. [...]

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One Healthand Advanced Biotechnology

2017-02

Nicolae Manolescu, Emilia Balint, Sabin Cinca, Calin Chirila

The merit of coagulating the various components of one-health concept and disseminating it in practice at largeis credited to the United States and especially to the two US structures, respectively ONE HEALTH COMMISSION coordinated by Mrs. Cheryl Stroud and ONE HEALTHINITIATIVE - with the excep-tional coordination of Dr. Bruce Kaplan, Dr. Laura Kahn, Dr. Lisa Conti and Prof. Gregory Gray from Duke University, Florida.

This concept has spread throughout the world, including Europe. The year 2014 represents the formalization of this concept in Europe under the coordination of the Federation of European Academies of Medicine (FEAM), with Prof. Dr. Bernard Charpentier, Prof. André Laurent Parodi and Prof. George Griffin as chairpersons. [...]

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The Cutaneous Adverse Events at the Site of Insulin Injections

2017-02

Rucsandra Danciulescu Miulescu, Georgeta Vacaru, Nicoleta Mindrescu

Cutaneous adverse events at the site of insulin injections include local allergic reactions to insulin (erythema, pruritus, and induration) and lipodystrophy The allergic reactions are usually short-lived, and resolve spontaneously within a few weeks [1]. Lipodystrophies are a group of diseases characterised by a morphological and/or functional impairment of the adipose tissue. Classification of lipodystrophy include genetic and acquired forms. Acquired forms can be generalized (Lawrence syndrome), partial (Barraguer-Simons syndrom, associated with sclerodermia or acquired immunodeficiency syndrome and antiretroviral therapy), or local (associated with drug: glucocorticoids, post-injection-insulin, somatostatin analogs, pegvisomant)[2]. Clinical forms of lipodystrophy include lipoatrophy and lipohypertrophy. [...]

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